肝脏CT动态增强扫描非刚性对位减影技术的质量评价

目的利用血管减影前后的吻合程度，探讨非刚性对位减影技术在肝脏CT动态增强检查中的质量评价。 方法收集2018年12月至2019年2月于中山大学附属第一医院行肝脏CT动态增强检查的50例患者资料，使用非刚性对位减影技术获得减影图像，对减影前后的图像质量进行评价，定性评价包括图像伪影情况及解剖错配程度，定量评价测量各血管（腹主动脉、肝右动脉、肝左动脉、门静脉主干、门静脉右支、门静脉左支）减影前后在动脉晚期、门静脉晚期的CT值。采用混合线性效应模型及拟合方程评估减影前后各血管的CT值曲线拟合程度。 结果减影后图像均无明显解剖结构错配导致的伪影，3名测量者一致性较高（ICC=0.844，P<0.001）。减影技术一定程度上会降低各血管的CT值，与强化分期不存在交互作用。无论是在动脉晚期还是门静脉晚期，减影前后各血管CT值走势一致，CT值变化曲线吻合。 结论非刚性对位减影技术可轻松实现肝脏CT动态增强检查的图像减影，并获得良好的图像质量。     

多参数磁共振成像诊断前列腺癌的现状及发展前景

正一、前列腺癌多参数磁共振成像的现状近年来国际、国内掀起了精准医学、无创诊断的多参数磁共振成像(multiparametric MRI,mpMRI)浪潮,利用影像图像,提取影片中的病灶影像特征,结合患者的临床数据,分析影像学潜在的基因组学、蛋白组学及其他病理生理学特征。在大数据的潮流当中,从大量影像检查的数据中     

两种术式对于胆道结石患者术后胆道压力与胃肠道功能研究

目的探讨微创手术和开腹手术治疗胆道结石患者的临床疗效及对胆道压力和胃肠道功能的影响，分析胆道压力与胃肠功能的相互关系。 方法回顾性分析2016年1月至2018年1月收治的124例胆道结石患者。开腹组60例患者采用开腹手术治疗，微创组64例患者采用腹腔镜下胆道镜内镜联合钬激光碎石术治疗。采用SPSS18.00统计软件分析，术中术后指标、炎性因子检测、术后胆道压测定和胃肠动力指标检测，以均数( ±s)形式录入，采用独立t检验；净石率、术后并发症比较采用χ²检验；胆道压力与胃肠动力指标相关性分析采用Spearman相关分析，以P<0.05表示差异有统计学意义。 结果微创组手术时间、住院天数、住院费用、净石率、并发症率均优于开腹组(P<0.05)；微创组术后3 d、 5 d血清IL－6、 IL－8、 TNF－α浓度、 MTL、 CCK、 VIP水平和胆道压力和均显著低于开腹组(P<0.05)；患者术后胆道压力与胃肠动力指标MTL、 CCK程负相关(r＝－0.632, －0.678; P均<0.05)；VIP水平与胆道压力程正相关(r＝0.712; P<0.05)。 结论腹腔镜下胆道镜内镜联合钬激光碎石术治疗胆道结石临床效果明显，术后机体炎症反、胆道压力、胃肠动力指标更优，且胆道压力与胃肠动力指标具有一定相关性。     

Are plain-language summaries included in published reports of evidence about physiotherapy interventions? Analysis of 4421 randomised trials,systematic reviews and guidelines on the Physiotherapy Evidence Database (PEDro)

BackgroundA plain-language summary is a short and clearly stated version of a study’s results using non-scientific vocabulary that provide many advantages for patients and clinicians in the process of shared decision-making.ObjectivesThe primary objective was to investigate the extent to which published reports of physiotherapy interventions provide plain-language summaries. We investigate as the secondary objectives if the available plain-language summaries are at a suitable reading level for a lay person and if inclusion of plain-language summaries in these reports is increasing over time and is associated with trial quality (i.e. PEDro score).Data sourcesAll 4421 randomised controlled trials (RCT), systematic reviews and clinical practice guidelines that included plain-language summaries indexed on Physiotherapy Evidence Database (PEDro) were included.Main outcome measuresProportion of published reports with plain-language summaries, Flesch Reading Ease Score (FRES) and the Flesch–Kincaid Grade Level (FKGL).ResultsThe number of published reports with a plain-language summary doubled in the last 6 years. From a total of 34,444 reports indexed on PEDro, only 4421 reports had English plain-language summaries. RCTs with plain-language summaries had higher PEDro scores than RCTs without plain-language summaries (mean difference = 0.8 points, 95%CI 0.7 to 0.8). Only 2% of reports were considered at a suitable reading level by the FKGL formula and 0.1% by the FRES formula.ConclusionsAlthough the publication of plain-language summaries is increasing over time, the current number corresponds to only 13% of all published reports. In addition the majority of plain-language summaries are written at an advanced reading level.     

Parental Guidance and Children’s Healthy Food Consumption: Integrating the Theory of Planned Behavior with Interpersonal Communication Antecedents

The study of parenting practices on child food consumption has often been characterized as having great utility but lacking in theory. In contrast, the theory of planned behavior (TPB) has often been suggested to be limited in its utility. To address these gaps, interpersonal constructs – the concepts of active parental guidance (e.g., nutrition education) and restrictive parental guidance (e.g., rule-setting) – were integrated as antecedents to the original TPB variables in predicting child fruits and vegetables (FV) consumption. We surveyed 210 child/adolescent participants, aged between 10 and 16 in Singapore. Results from structural equation modeling showed that the integrative TPB model displayed an acceptable fit. Parental active guidance was associated with all three proximal predictors of behavior. Our results suggest that there are promising contributions to the theory of planned behavior in predicting child food consumption behavior by considering interpersonal antecedents.